New Source of Rutin from the Flowers of Cordia lutea (Boraginaceae)
Edmundo Arturo Venegas-Casanova *
Faculty of Pharmacy and Biochemistry, National University of Trujillo, Perú.
Segundo Guillermo Ruiz Reyes
Faculty of Pharmacy and Biochemistry, National University of Trujillo, Perú.
José Gilberto Gavidia Valencia
Faculty of Pharmacy and Biochemistry, National University of Trujillo, Perú.
Cosavalente Burgos Kevin Steve
Faculty of Pharmacy and Biochemistry, National University of Trujillo, Perú.
Yuri Freddy Curo Vallejos
Faculty of Pharmacy and Biochemistry, National University of Trujillo, Perú.
Juan Ernesto Valdiviezo Campos
Faculty of Pharmacy and Biochemistry, National University of Trujillo, Perú.
Santiago Moisés Benites Castillo
César Vallejo University, Trujillo, Perú.
Armando Cuéllar Cuéllar
Faculty of Pharmacy and Foods, Havana University, Cuba.
*Author to whom correspondence should be addressed.
Abstract
The native species Cordia lutea, is used in Peru by folk medicine in the treatment of liver diseases such as jaundice and others. From fluid extract of the flowers, flavonoid quercetin-3-O-rhamnoglucoside (rutin) was isolated and identified. The relative purity was assay by HPLC and structural elucidation using 1H and 13C NMR spectral data in comparison with literature. Quercetin-3-O-rhamnoglucoside (rutin), was the major component of the fluid extract obtained from C. lutea flowers, with a relative purity, after crystallization, of 97.55% and 8% yield from the extract. As a conclusion for this investigation, it is important to note, that with the fluid extract from the flowers of C. lutea it is possible the isolation of the flavonoid quercetin-3-O-rhamno glucoside (rutin) with high purity and yield. This compound was not previously described in the flowers of this plant species.
Keywords: Cordia lutea flowers, Rutin